Gene editing

Viral vector start-up aims to tackle gene therapy Longevity bottleneck

64x Bio will use proprietary platform to spearhead cell and gene therapy manufacture. Gene therapy can be a fantastic tool for targeting chronic age-related conditions;...

eGenesis advances xenotransplantation research

Reducing waiting lists and treating diabetes – eGenesis progresses xeno without the paradox. Recently we covered eGenesis' progress in its xenotransplantation research, as it attempts...

A novel approach to aging – epigenetics and cellular variability

Cellular stochasticity and epigenetic drift in aging can not only provide Longevity targets but also give a deeper understanding of the origins of cancer. Current...

eGenesis progresses xenotransplantation toward type 1 diabetes

Gene-edited pancreatic islet cells: an important first step towards human clinical trials for type 1 diabetes. eGenesis, a biotech company using gene-editing technologies for the...

Epigenetic regulation of protein homeostasis following DNA damage

Recent study identifies critical regulator of protein biosynthesis recovery and homeostasis required for Longevity. Unresolved DNA damage caused by intrinsic and environmental factors accumulates during...

Epigenetic reprogramming: the road to reversing time

Epigenetic modifications – also known as “aging clocks” – have emerged as promising markers of aging and accurate predictors of age-related diseases; they're a hot...

$85m funding for epigenetic platform technology

Omega Therapeutics secures $85m to carry out clinical trials into epigenetic treatments for five key disease areas – and potentially for Covid-19.  While you might...

New CRISPR-free gene-editing tool exploits bacterial warfare

New tool uses an interbacterial toxin to achieve precise mitochondrial gene editing without CRISPR side-effects. Mitochondria – often called the "powerhouse" of the cell –...

eGenesis’ xenotransplantation trials move closer to in-human

eGenesis' groundbreaking xenotransplantation work with Massachusetts General Hospital to be expanded through additional collaboration. eGenesis has announced it is expanding its research collaboration with the...

Wyss Institute and Cytosurge collaborate on CRISPR tech

The Wyss Institute at Harvard is joining forces with Swiss Biotech Cytosurge in a bid to improve CRISPR-based multiplexed gene editing with a single-cell...

Longevity2020: Day 5 Recap

On Friday, the Longevity2020 online conference drew to a close, and the final day explored what people can be doing today to address their...

Longevity2020: Day 2 recap

Yesterday at Longevity2020 was all about rejuvenation therapies, bringing together some of the world’s leading luminaries in the fight against aging. Things kicked off with...

BioViva to spin out its R&D and bioinformatics

CEO in the front-line: Liz Parrish talks gene therapy, patient data and funding. From academics and entrepreneurs to engineers and technologists, the battle against aging...

Reprogram, rejuvenate, rewind: spinout

Soaking up Longevity - a Stanford University team has rejuvenated aging human cells with a novel protein "bath" and formed a spinout. Researchers at Stanford...

Better, faster, stronger CRISPR

Cytosurge claims to be able to make CRISPR “better and faster than anybody else on single cell level” - seeking investment to evolve world’s smallest syringe...

Fishing for regenerative therapies

Talking Longevity, indication expansion, killifish and regeneration with Dr Aric Rogers from the MDI Biological Laboratory. Nestled on the picturesque coastline of Maine, USA, the...

Human CRISPR trial heralds Longevity success

Trial finds not only that gene-edited immune cells are safe, but that they survive and thrive after being placed into patients suffering from advanced...

Rejuvenate Bio teaches old dogs new tricks

A combination gene therapy developed by the Wyss Institute and Harvard Medical School is set to treat several age-related conditions in dogs, extending their...

23andMe redundancies: DNA test market decline?

Could layoffs at 23andMe be a sign that the consumer appetite for genetic testing is declining? We expect consumer markets to transition to more...

UK Gov releases human germline editing brief

Human Germline Genome Engineering is a highly controversial area – altering genes so that changes are passed on to all descendants.  Just because we...
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