A recent article provides an integrative view of the hallmarks of aging and the extensive network linking them: time to join-up our thinking?
Mitochondria are...
Mounting evidence shows an important role for calcium and ROS interplay in fine-tuning cellular signalling and physiological responses, thereby regulating aging and age-related disorders....
A recent study shows an important role for GDF15 in preventing aging-induced metabolic phenotypes by modulating systemic inflammatory responses in humans and mice.
Dysfunction of...
New tool uses an interbacterial toxin to achieve precise mitochondrial gene editing without CRISPR side-effects.
Mitochondria – often called the "powerhouse" of the cell –...
Co-founder of Longevity-focused investment firm shows you can target aging AND appeal to biotech investors.
Founded in 2016, Berlin and Boston-based Apollo already boasts an...
Researchers use metformin to repair broken cell machinery and drastically lower dangerous inflammation.
Inflammaging is one of the latest Longevity buzzwords; it has been around...
A recent Chinese study has identified two novel anti-aging targets that accelerate aging by suppressing the expression of genes involved in mitochondrial function maintenance: promoting...
Understanding the trigger for cellular senescence could help to forge new treatments for Longevity, stopping aging before it's started.
Cellular senescence is a double-edged sword;...
New study shows that two experimental drugs can reverse age-related cognitive impairment and potentially treat Alzheimer's disease, by restoring mitochondrial function in the aging...
Teenage founder of Canadian start-up Biotein hunts a universal phenotype for senescent cells.
Nina Khera (pictured above, first left) became interested in the challenge of...
Elysium Health is to study correlations between epigenetic aging and amounts of NAD+ and other biomarkers in a new clinical trial.
Fresh on the back...
There are few voices in Longevity research as distinctive as Dr Nir Barzilai’s.
Brimming with jokes and references, his sentences digress and then return to...
Report finds that anti-diabetic drug metformin could make exercise less effective at improving health but aging researchers remain upbeat.
Metformin has been, for a long...
Parkinson’s UK charity strikes a £1 million deal partnership with NRG Therapeutics for developing drugs aimed at mitochondria.
The UK’s leading charity for this disease...
Scientists find promising pathway that links mitochondrial damage from smoking and drinking to osteoporosis.
The risk factors of osteoporosis, an age-related disease, have long been...
