Indication expansion

From machines to animals to humans

Exclusive with Prof Joao Pedro de Magalhaes: talking AI, indication expansion and animal models. “Will you still need me, will you still feed me, when...

Metabolic aging, fasting and metformin

The presence of a “metabolic clock” that regulates aging involves the accumulation of metabolic alterations and a decline in metabolic homeostasis and biological fitness. An...

LSD = Longevity (and) stalled dementia?

New York-based biotech company Eleusis has completed a phase 1 trial of the psychedelic drug LSD and is moving forward to phase 2. Could...

Fishing for regenerative therapies

Talking Longevity, indication expansion, killifish and regeneration with Dr Aric Rogers from the MDI Biological Laboratory. Nestled on the picturesque coastline of Maine, USA, the...

Rejuvant shows positive early results in humans

Anecdotal results for dietary supplement show significant improvements in biological age and major reductions in key blood biomarkers. In our recent interview with leading Longevity...

Prof Brian Kennedy: Talking biomarkers and interventions

“We're not trying to make billionaires live longer, we're trying to make everybody live longer.” When it comes to thought leaders in the Longevity sector,...

Talking pipeline with resTORbio’s Joan Mannick

While Phase 3 trial of RTB101 for respiratory illness did not meet primary endpoint, company presses-on with Parkinson’s trial for TORC1 inhibitor: Results expected...

It’s all in the numbers; small sets of numbers

AI start-up NetraMark targets $3 million seed round while identifying that an exciting repurposing candidate has potential for indication expansion into Longevity. “I won’t tell you...

NetraMark and Juvenescence extend collaboration

Partnership sees AI platform expanded into drug repurposing and discovery. Canadian AI technology firm NetraMark yesterday announced the extension of its NetraPharma collaboration agreement with...

Calico licenses memory-enhancing drug ISRIB

A new drug known as ISRIB which reverses Down's Syndrome memory deficits in mice has been licensed to Google’s Calico for aging research. In 2016...

New study shows rapamycin slows Alzheimer’s

A new study from UT Health San Antonio suggests the drug rapamycin may be able to slow the rate of brain-related blood flow decreases. The...

Anti-aging metformin brain drug works – but only in women!

Could metformin be made for women? The Longevity drug on the side of girl power. A new study has demonstrated that while metformin may have...

World’s first anti-aging TAME trial gets green-light

Groundbreaking TAME trial, which directly targets aging as an endpoint, finally begins this November, reveals lead clinician Dr Nir Barzilai. After closing the final $40m...

Taking life-extending drug Rapamycin to the next level

Life extension studies fly the flag for Rapamycin – a clever drug with humble origins – now a US research team is taking matters...

Metformin could limit the health benefits of exercise

Report finds that anti-diabetic drug metformin could make exercise less effective at improving health but aging researchers remain upbeat. Metformin has been, for a long...

Aspirin – the original Longevity wonder drug

Aspirin could reduce healthcare spending by nearly $700 billion in the US alone – and it's already in mass-production. Acetylsalicylic acid, orginally extracted from willow...

Latest articles

Join me at my 100th birthday party in 2049!

We speak with GRG's Johnny Adams, a key contributor to the Longevity2020 online conference, about his quest for more healthy years. One of the speakers at this month’s...

Call for consensus in defining biological aging

We speak with a key contributor to the Longevity2020 online conference about biological aging. UK start-up AgeCurve is focused on the measurement of aging and...

Low-dose rapamycin to protect elderly from COVID-19

Longevity researcher proposes clinical trials for low-dose rapamycin (and other geroprotectors) to protect the elderly from COVID-19. The UK's Biogerontology Research Foundation today announced the...

Reprogram, rejuvenate, rewind: spinout

Soaking up Longevity - a Stanford University team has rejuvenated aging human cells with a novel protein "bath" and formed a spinout. Researchers at Stanford...

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