rejuvant life tabs

Aubrey de Grey: Methuselarity by 2035 – and it’ll be free

Latest articles

A single source for longevity nutrition data

Edamam co-founder talks bringing nutrition into the digital world and seeking funding for expansion in food as medicine. When it comes to food nutrition data,...

The Sheekey Science Show – Senotherapeutics

Senotherapeutics are therapeutics strategies that target cellular senescence. They can work by killing senescent cells (senolytics), inhibiting the proinflammatory secretory phenotype of senescent cells (senomorphics)...

Michael Greve commits €300m for rejuvenation start-ups

The founder of Forever Healthy has committed €300 million to advance rejuvenation biotech start-ups – plus exclusive insights from Michael Greve. Michael Greve, founder of...

Capsida Biotherapeutics emerges from stealth with $140m

Versant Ventures and Westlake Village BioPartners launch next-generation gene therapy company with $50m series A; AbbVie collaboration provides $90m for gene therapies for CNS...

Most read

New NAD+ boosting longevity supplement hits the market

Elevant Prime dietary supplement contains a “high purity” form of NMN that has completed safety and toxicology testing. New York based health and wellness brand...

David Sinclair to co-chair $200 million biotech SPAC

Christian Angermayer's Frontier Acquisition Corp. holds significant longevity interest with David Sinclair and Peter Attia as Co-Chairs of the Board. Frontier Acquisition Corporation, a special...

JUVICELL sets sights on lifespan and healthspan

Ten ingredients, one capsule. JUVICELL is on a mission to deliver an all-in-one longevity supplement. Far from just supplementing their diet to ensure an adequate...
Supplement report

Editor's picks

A single source for longevity nutrition data

Edamam co-founder talks bringing nutrition into the digital world and seeking funding for expansion in food as medicine. When it comes to food nutrition data,...

The Sheekey Science Show – Senotherapeutics

Senotherapeutics are therapeutics strategies that target cellular senescence. They can work by killing senescent cells (senolytics), inhibiting the proinflammatory secretory phenotype of senescent cells (senomorphics)...

Michael Greve commits €300m for rejuvenation start-ups

The founder of Forever Healthy has committed €300 million to advance rejuvenation biotech start-ups – plus exclusive insights from Michael Greve. Michael Greve, founder of...
Rejuvant

Aubrey de Grey tells Longevity.Technology the revolution is coming, and everyone will be eligible.

“I now think there is a 50% chance that we will reach longevity escape velocity by 2036. After that point (the “Methuselarity”), those who regularly receive the latest rejuvenation therapies will never suffer from age-related ill-health at any age.” So said eminent biomedical gerontologist and co-founder of the SENS Research Foundation, Dr Aubrey de Grey recently on Twitter.

Longevity.Technology: the idea of a Longevity Escape Velocity, or LEV, is one that is really gaining traction; it is the point where for every year we survive, we gain an extra year. As research continues to progress, life expectancy will continually be extended longer than the time that is passing. Is indefinite life extension on the cards and who does want to live forever?

Check out my fascinating quick-fire interview with Aubrey:

Aubrey de Grey on …

Mouse rejuvenation translated to humans:

We are considerably closer to robust mouse rejuvenation than we were 10 years ago … the gap between the achievement of robust mouse rejuvenation and the achievement of robust human rejuvenation is also, in my view, coming down quite fast.

Accuracy of the 2035 Methuselarity date:

When I make a prediction of any nature, about timeframes, I am aggregating all of the steps and looking at all of the potential bottlenecks, the potential delays, and evaluating what I feel they’re likely to be in terms of magnitude.

Longevity escape velocity – how young do you need to be to benefit?

Elevant

I think that actually the chance of somebody alive today benefiting from the Methuselarity and never getting sick as a result of how long ago they were born, that chance is much higher than 50%. It’s probably 80% or 90%. At this point, the chance of someone who is let’s say, 53, of reaching that is probably 40 or 50%.

Stem cell therapies and senolytics:

I absolutely think that stem cell therapies are going to be, literally, an essential pillar of the portfolio of damage repair approaches that we pursue … and indeed, at SENS Research Foundation, we have a study ongoing right now where we are combining stem cell treatment with senolytic drugs to kill senescent cells.

What’s the cost of LEV: is this just for rich people?

What’s it going to cost to the end-user: zero. And the reason is that aging is so expensive that it would be economically suicidal for any country not to make these things available, irrespective of ability to pay, to everybody who’s old enough to need them. And thereby to allow those therapies to pay for themselves many times over really quickly, just by keeping the elderly, able-bodied, and healthy, and in a position to contribute wealth.

Image credit: SENS Research Foundation

2 COMMENTS

Comment on this article

Phil Newman
Editor-in-Chief Phil is Editor-in-Chief Longevity.Technology and founder of First Longevity which brings together international investors and Longevity start-ups.

In his career, Phil has held c-level management positions; applying his marketing and business development expertise into these tech sectors: Longevity; IoT; AI; Medical Devices; Biopharma; 3D Manufacturing; Smartgrid and Sustainability.
Rejuvant

Most popular

New NAD+ boosting longevity supplement hits the market

Elevant Prime dietary supplement contains a “high purity” form of NMN that has completed safety and toxicology testing. New York based health and wellness brand...

David Sinclair to co-chair $200 million biotech SPAC

Christian Angermayer's Frontier Acquisition Corp. holds significant longevity interest with David Sinclair and Peter Attia as Co-Chairs of the Board. Frontier Acquisition Corporation, a special...

JUVICELL sets sights on lifespan and healthspan

Ten ingredients, one capsule. JUVICELL is on a mission to deliver an all-in-one longevity supplement. Far from just supplementing their diet to ensure an adequate...

Is nicotinamide riboside a safe and effective way to combat aging?

ChromaDex executive highlights the importance of clinical studies to prove the benefits of NAD+ boosting compound. ChromaDex is the company behind the popular healthy aging...
Supplement report

Related articles

The Sheekey Science Show – Senotherapeutics

Senotherapeutics are therapeutics strategies that target cellular senescence. They can work by killing senescent cells (senolytics), inhibiting the proinflammatory secretory phenotype of senescent cells (senomorphics)...

Exclusive interview with Alex Zhavoronkov

Insilico CEO on spreading the longevity message – the time is now. Dr Alex Zhavoronkov is the CEO and co-founder of Insilico Medicine, a pioneering AI...

The Sheekey Science Show – Senolytics

This new senescence biomarker may help evaluate senolytic efficacy. Senescent cells, also known as "zombie cells", accumulate with age. There are many different ways in...

Charles Brenner: the journey from NR to Tru Niagen

Dr Charles Brenner, the developer of the intellectual property behind ChromaDex's Tru Niagen, on all things metabolism, NAD and NR clinical trials. Longevity.Technology: Following the...

The Sheekey Science Show – Precision Medicine

What to expect for Precision medicine by 2030? All of us are unique. What may good for one persons health may be terrible for another's....
Supps report ad middle